Irene was born and raised in Switzerland where she studied at ETH Zurich, with the exception of a one year escape to the University of New South Wales in Sydney, Australia. Along the way she became intrigued by the atomic-resolution that structural biology offered to understand how proteins and other biomolecules operate. For her PhD she joined the lab of Frédéric Allain at ETH Zurich where she got hooked on NMR, RNA biology and splicing. After graduating, Irene moved to San Francisco to join Hiten Madhani's lab at UCSF. There she set up a CRISPR-Cas9 base editing system in haploid cells to study splicing using forward genetic screens, supported by fellowships from the Swiss National Science Foundation.

Since September 2024, Irene is an independent junior group leader at the Institute of Molecular Infection Biology at the University of Würzburg.

In her free time, Irene used to try visiting as many of the US national parks as possible to camp there and hike. She is now looking forward to (re-)discovering beautiful spots across Germany and Europe.

I began my path into science with a Bachelor's degree in Molecular Life Science at the University of Lübeck, where I developed a strong appreciation for scientific research and its ability to uncover fundamental biological processes. During this time, I also participated in an Erasmus exchange at the University of Stockholm, where I was first introduced to the structure–function relationships of proteins—and quickly became fascinated by the insights offered by structural biology.

I continued my education with a Master's program in Biochemistry and Biophysics at the Universities of Freiburg and Strasbourg. For my Master's thesis, I joined the research group of Dr. Natacha Rochel at the IGBMC Strasbourg, where I used protein biochemical and biophysical methods to investigate interactions of nuclear receptors.

In the Beusch lab, I’m excited to expand my skills and knowledge in molecular and RNA biology by joining a project focused on proteins involved in early spliceosome assembly.

Outside of he lab, I’m currently trying to improve my badminton skills and enjoy engaging in conversations about literature, cinema, television, and political and social topics.

Farimehr began her scientific journey with a Bachelor’s degree in Medical Laboratory Sciences in Iran, where she developed an interest in molecular biology. To deepen her understanding, she pursued a Master’s in Molecular Biology at the University of Padua in Italy. During this time, an internship in Luca Scorrano’s lab, known for its pioneering work on mitochondrial dynamics and metabolism, further inspired her to continue this path.

As part of an Erasmus exchange, she moved to Würzburg, where she completed her master’s thesis at the DZHI in Professor Christoph Mack’s group, gaining hands-on experience in advanced molecular techniques. Following her thesis, she joined the Litvinukova’s group at WüSi, where she spent a year mastering methods like single-cell nuclei isolation and hashing for sequencing, refining her skills in high-throughput molecular analysis.

Beyond the lab, she is enthusiastic about meeting new people from diverse cultures and enjoys spending time in nature, especially picnicking in the sunshine.