* co-first author, ‡ co-corresponding
2024
Damberger FF, Krepl M, Arora R, Beusch I, Maris C, Dorn G, Šponer J, Ravindranathan S, Allain FHT (2024) N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition Nucleic Acids Res 52(17):10683-10704
Beusch I and Madhani HD (2024) Understanding the dynamic design of the spliceosome. TIBS 49(7):583-595 review
2023
Beusch I, Rao B, Studer MK, Luhovska T, Šukytė V, Lei S, Oses-Prieto J, SeGraves E, Burlingame A, Jonas S, and Madhani HD (2023) Targeted high-throughput mutagenesis of the human spliceosome reveals its in vivo operating principles. Mol Cell 83(14):2578-2594
Moursy A, Cléry A, Gerhardy S, Betz KM, Rao S, Mazur J, Campagne S, Beusch I, Duszczyk M, Robinson MD, Panse VG, Allain FHT (2023) RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. Nat. Commun. 14, 7166
2021
Sales-Lee J, Perry DS, Bowser BA, Diedrich JK, Rao B, Beusch I, Yates JR III, Roy SW, Madhani HD (2021) Coupling of spliceosome complexity to intron diversity. Curr. Biol. 31, 4898-4910.e4
2020
Maris C, Jayne S, Damberger FF, Beusch I, Dorn G, Ravindranathan S, Allain FHT (2020) A transient α-helix in the N-terminal RNA recognition motif of polypyrimidine tract binding protein senses RNA secondary structure. Nucleic Acids Res. 48, 4521–4537
2017
Beusch I*, Barraud P*, Moursy A, Cléry A, Allain FHT (2017) Tandem hnRNP A1 RNA recognition motifs act in concert to repress the splicing of survival motor neuron exon 7. eLife 6, e25736